||IF, ICC, IHC-P
||Human, Mouse, Rat
||FOR RESEARCH USE ONLY (RUO).
||Mouse monoclonal antibody anti-Neprilysin is suitable for use in Immunofluorescence, Immunocytochemistry and Immunohistochemistry research applications.
||PBS, pH 7.4, 0.5% BSA, 0.02% Sodium Azide and 50% Glycerol.
||The antibody was isolated from ascitic fluid by immunoaffinity chromatography using antigens coupled to agarose beads.
||IF 1:50-200WB 500-2000:1:200
||Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
||MME monoclonal antibody (Neprilysin) binds to endogenous Neprilysin.
||Synthetic peptide of CD10
| Function || Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF) and brain natriuretic factor (BNP(1-32)). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers. |
| Protein Name || NeprilysinAtriopeptidaseCommon Acute Lymphocytic Leukemia AntigenCallaEnkephalinaseNeutral Endopeptidase 24.11NepNeutral EndopeptidaseSkin Fibroblast ElastaseSfeCd Antigen Cd10 |
| Database Links || Reactome: R-HSA-2022377Reactome: R-HSA-6798695 |
| Cellular Localisation || Cell MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names || Anti-Neprilysin antibodyAnti-Atriopeptidase antibodyAnti-Common Acute Lymphocytic Leukemia Antigen antibodyAnti-Calla antibodyAnti-Enkephalinase antibodyAnti-Neutral Endopeptidase 24.11 antibodyAnti-Nep antibodyAnti-Neutral Endopeptidase antibodyAnti-Skin Fibroblast Elastase antibodyAnti-Sfe antibodyAnti-Cd Antigen Cd10 antibodyAnti-MME antibodyAnti-EPN antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance