Anti-MLIP antibody (216-266 aa) (STJ196013)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human MLIP at the amino acid range 216-266
General Information
| Short Description | Rabbit polyclonal anti-Muscular LMNA-interacting protein (216-266 aa) for use in WB, ELISA and IHC in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA/IHC |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000IHC-P 1:50-300ELISA 2000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MLIP |
| Gene ID | 90523 |
| Uniprot ID | MLIP_HUMAN |
| Immunogen | Synthesized peptide derived from the human MLIP at the amino acid range 216-266 |
| Immunogen Region | 216-266 aa |
| Specificity | This antibody detects endogenous levels of MLIP at Human/Mouse |
Additional Info
| Function | Required for myoblast differentiation into myotubes, possibly acting as a transcriptional regulator of the myogenic program. Required for cardiac adaptation to stress through integrated regulation of the AKT/mTOR pathways and FOXO1. Regulates cardiac homeostasis and plays a role in the protection against cardiac hypertrophy. Binds chromatin. May act as a transcriptional cofactor for ISL1, repressing its transcriptional activity. May also repress MYOCD transcriptional activity. |
| Protein Name | Muscular Lmna-Interacting ProteinCardiac Isl1-Interacting ProteinCipMuscular-Enriched A-Type Laminin-Interacting Protein |
| Database Links | |
| Cellular Localisation | NucleusNucleus EnvelopePml BodyCytoplasmCytosolCell MembraneSarcolemmaPeripheral Membrane ProteinCytoplasmic Side |
| Alternative Antibody Names | Anti-Muscular Lmna-Interacting Protein antibodyAnti-Cardiac Isl1-Interacting Protein antibodyAnti-Cip antibodyAnti-Muscular-Enriched A-Type Laminin-Interacting Protein antibodyAnti-MLIP antibodyAnti-C6orf142 antibodyAnti-Cip antibody |
Information sourced from Uniprot.org