| Host: | Rabbit |
| Applications: | WB/ELISA/IHC |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Muscular LMNA-interacting protein (216-266 aa) is suitable for use in Western Blot, ELISA and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000IHC-P 1:50-300ELISA 2000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MLIP |
| Gene ID: | 90523 |
| Uniprot ID: | MLIP_HUMAN |
| Immunogen Region: | 216-266 aa |
| Specificity: | This antibody detects endogenous levels of MLIP at Human/Mouse |
| Immunogen: | Synthesized peptide derived from the human MLIP at the amino acid range 216-266 |
| Function | Required for myoblast differentiation into myotubes, possibly acting as a transcriptional regulator of the myogenic program. Required for cardiac adaptation to stress through integrated regulation of the AKT/mTOR pathways and FOXO1. Regulates cardiac homeostasis and plays a role in the protection against cardiac hypertrophy. Binds chromatin. May act as a transcriptional cofactor for ISL1, repressing its transcriptional activity. May also repress MYOCD transcriptional activity. |
| Protein Name | Muscular Lmna-Interacting ProteinCardiac Isl1-Interacting ProteinCipMuscular-Enriched A-Type Laminin-Interacting Protein |
| Cellular Localisation | NucleusNucleus EnvelopePml BodyCytoplasmCytosolCell MembraneSarcolemmaPeripheral Membrane ProteinCytoplasmic Side |
| Alternative Antibody Names | Anti-Muscular Lmna-Interacting Protein antibodyAnti-Cardiac Isl1-Interacting Protein antibodyAnti-Cip antibodyAnti-Muscular-Enriched A-Type Laminin-Interacting Protein antibodyAnti-MLIP antibodyAnti-C6orf142 antibodyAnti-Cip antibody |
Information sourced from Uniprot.org