Anti-MLD antibody [R03-5D2] (STJA0034570)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide of human MLD
General Information
| Short Description | Rabbit monoclonal anti-MLD for use in WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R03-5D2 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.3 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000 |
| Formulation | 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | DEGS1 |
| Gene ID | 8560 |
| Uniprot ID | DEGS1_HUMAN |
| Immunogen | A synthetic peptide of human MLD |
Additional Info
| Tissue Specificity | Ubiquitous. |
| Post Translational Modifications | Myristoylation can target the enzyme to the mitochondria leading to an increase in ceramide levels. |
| Function | Has sphingolipid-delta-4-desaturase activity. Converts D-erythro-sphinganine to D-erythro-sphingosine (E-sphing-4-enine). Catalyzes the equilibrium isomerization of retinols. |
| Protein Name | Sphingolipid Delta(4-Desaturase Des1Cell Migration-Inducing Gene 15 ProteinDegenerative Spermatocyte Homolog 1Dihydroceramide Desaturase-1Membrane Lipid DesaturaseRetinol Isomerase |
| Database Links | Reactome: R-HSA-1660661Reactome: R-HSA-6798695 |
| Cellular Localisation | Mitochondrion MembraneEndoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Sphingolipid Delta(4-Desaturase Des1 antibodyAnti-Cell Migration-Inducing Gene 15 Protein antibodyAnti-Degenerative Spermatocyte Homolog 1 antibodyAnti-Dihydroceramide Desaturase-1 antibodyAnti-Membrane Lipid Desaturase antibodyAnti-Retinol Isomerase antibodyAnti-DEGS1 antibodyAnti-DES1 antibodyAnti-MLD antibodyAnti-MIG15 antibody |
Information sourced from Uniprot.org