Anti-MLC1 antibody (179-193) (STJ72971)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-MLC1 (179-193) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Applications | Pep-ELISA/WB/IHC |
| Host | Goat |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:128000.WB: Approx 70kDa band observed in Human Brain (Hippocampus) lysates (calculated MW of 41.1kDa according to NP_055981.1). The observed molecular weight corresponds to earlier findings in l |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | MLC1 |
| Gene ID | 23209 |
| Uniprot ID | MLC1_HUMAN |
| Accession Number | NP_055981.1 |
| Immunogen Region | 179-193 |
| Immunogen Sequence | SDSANILDEVPFPAR |
| Specificity | Reported variants represent identical protein: NP_631941.1, NP_055981.1. |
Additional Info
| Function | Transmembrane protein mainly expressed in brain atrocytes that may play a role in transport across the blood-brain and brain-cerebrospinal fluid barriers. Regulates the response of astrocytes to hypo-osmosis by promoting calcium influx. May function as regulatory protein of membrane protein complexes such as ion channels (Probable). |
| Protein Name | Membrane Protein Mlc1Megalencephalic Leukoencephalopathy With Subcortical Cysts Protein 1 |
| Cellular Localisation | MembraneMulti-Pass Membrane ProteinCell MembraneCytoplasmPerinuclear RegionEndoplasmic Reticulum |
| Alternative Antibody Names | Anti-Membrane Protein Mlc1 antibodyAnti-Megalencephalic Leukoencephalopathy With Subcortical Cysts Protein 1 antibodyAnti-MLC1 antibodyAnti-KIAA0027 antibodyAnti-WKL1 antibody |
Information sourced from Uniprot.org