| Short Description : | Rabbit polyclonal anti-Homeobox protein MIXL1 (90-170 aa) for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MIXL1 |
| Gene ID: | 83881 |
| Uniprot ID: | MIXL1_HUMAN |
| Immunogen: | Synthesized peptide derived from the human protein at the amino acid range 90-170 |
| Immunogen Region: | 90-170 aa |
| Specificity: | MIXL1 Polyclonal Antibody detects endogenous levels of protein. |
| Post Translational Modifications | Phosphorylated at multiple sites. |
| Function | Transcription factor that play a central role in proper axial mesendoderm morphogenesis and endoderm formation. Required for efficient differentiation of cells from the primitive streak stage to blood, by acting early in the recruitment and/or expansion of mesodermal progenitors to the hemangioblastic and hematopoietic lineages. Also involved in the morphogenesis of the heart and the gut during embryogenesis. Acts as a negative regulator of brachyury expression. |
| Protein Name | Homeobox Protein Mixl1Homeodomain Protein MixHmixMix1 Homeobox-Like Protein 1Mix.1 Homeobox-Like Protein |
| Database Links | Reactome: R-HSA-9754189Reactome: R-HSA-9823730 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Homeobox Protein Mixl1 antibodyAnti-Homeodomain Protein Mix antibodyAnti-Hmix antibodyAnti-Mix1 Homeobox-Like Protein 1 antibodyAnti-Mix.1 Homeobox-Like Protein antibodyAnti-MIXL1 antibodyAnti-MIXL antibody |
Information sourced from Uniprot.org
