Anti-MIXL1 antibody (185-232 aa) (STJ13101417)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide from aa region 185-232 of human MIXL1 conjugated to blue carrier protein was used as the antigen. The peptide shares 94% identity with mouse sequence.
General Information
| Short Description | Rabbit polyclonal anti-MIXL1 (185-232 aa) for use in IHC and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG purified |
| Dilution Range | IHC, WB (confirmed by recombinant protein). A dilution of 1:300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Formulation | Lyophilised |
| Storage Instruction | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Target Information
| Gene Symbol | MIXL1 |
| Gene ID | 83881 |
| Uniprot ID | MIXL1_HUMAN |
| Immunogen | A synthetic peptide from aa region 185-232 of human MIXL1 conjugated to blue carrier protein was used as the antigen. The peptide shares 94% identity with mouse sequence. |
| Immunogen Region | 185-232 aa |
| Specificity | Specific for MIXL1. |
Additional Info
| Post Translational Modifications | Phosphorylated at multiple sites. |
| Function | Transcription factor that play a central role in proper axial mesendoderm morphogenesis and endoderm formation. Required for efficient differentiation of cells from the primitive streak stage to blood, by acting early in the recruitment and/or expansion of mesodermal progenitors to the hemangioblastic and hematopoietic lineages. Also involved in the morphogenesis of the heart and the gut during embryogenesis. Acts as a negative regulator of brachyury expression. |
| Protein Name | Homeobox Protein Mixl1Homeodomain Protein MixHmixMix1 Homeobox-Like Protein 1Mix.1 Homeobox-Like Protein |
| Database Links | Reactome: R-HSA-9754189Reactome: R-HSA-9823730 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Homeobox Protein Mixl1 antibodyAnti-Homeodomain Protein Mix antibodyAnti-Hmix antibodyAnti-Mix1 Homeobox-Like Protein 1 antibodyAnti-Mix.1 Homeobox-Like Protein antibodyAnti-MIXL1 antibodyAnti-MIXL antibody |
Information sourced from Uniprot.org