| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-MIXL1 (150-232) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MIXL1 |
| Gene ID: |
83881 |
| Uniprot ID: |
MIXL1_HUMAN |
| Immunogen Region: |
150-232 |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 150-232 of human MIXL1 (NP_114150.1). |
| Immunogen Sequence: |
QPLARPEIILNHCAPGTETK CLKPQLPLEVDVNCLPEPNG VGGGISDSSSQGQNFETCSP LSEDIGSKLDSWEEHIFSAF GNF |
| Tissue Specificity | Restricted to progenitors and secondary lymph tissues. In normal hematopoiesis, it is restricted to immature B- and T-lymphoid cells. Present in differentiating embryonic stem cells (at protein level). |
| Post Translational Modifications | Phosphorylated at multiple sites. |
| Function | Transcription factor that play a central role in proper axial mesendoderm morphogenesis and endoderm formation. Required for efficient differentiation of cells from the primitive streak stage to blood, by acting early in the recruitment and/or expansion of mesodermal progenitors to the hemangioblastic and hematopoietic lineages. Also involved in the morphogenesis of the heart and the gut during embryogenesis. Acts as a negative regulator of brachyury expression. |
| Protein Name | Homeobox Protein Mixl1Homeodomain Protein MixHmixMix1 Homeobox-Like Protein 1Mix.1 Homeobox-Like Protein |
| Database Links | Reactome: R-HSA-9754189Reactome: R-HSA-9823730 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Homeobox Protein Mixl1 antibodyAnti-Homeodomain Protein Mix antibodyAnti-Hmix antibodyAnti-Mix1 Homeobox-Like Protein 1 antibodyAnti-Mix.1 Homeobox-Like Protein antibodyAnti-MIXL1 antibodyAnti-MIXL antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
