| Host: |
Mouse |
| Applications: |
IHC-P/IHC-F |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Mouse monoclonal antibody anti-Microphthalmia Transcription Factor is suitable for use in Immunohistochemistry and Immunohistochemistry research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
34CA5 |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG1k |
| Formulation: |
Tissue culture supernatant with 15mM Sodium azide |
| Dilution Range: |
IHC-P 1:10-1:20IHC-F |
| Storage Instruction: |
Store at 2-8°C upon receipt. |
| Immunogen: |
Prokaryotic recombinant protein corresponding to 111 amino acids of the N-terminal region of the MITF-M molecule |
| Background | Microphthalmia transcription factor (MITF) gene product, a nuclear transcription factor of the basic-helix-loop-helix type, is thought to play a role in the regulation of genes encoding the enzymes necessary for melanogenesis. These include tyrosinase, TRP-1 and TRP-2. MITF is critical for the embryonic development and postnatal viability of melanocytes. The melanocyte-specific isoform of microphthalmia transcription factor MITF-M, is reported to be expressed in normal and malignant melanocytes. The other isoforms, MITF-A, MITF-C and MITF-H, differ structurally at the N-terminus from MITF-M. |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![Anti-MiTF antibody [C5/D5] (STJ16100393)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/149110/346731/STJ16100393_1__10443.1681998821.jpg?c=1 "Anti-MiTF antibody [C5/D5] (STJ16100393)")
