Anti-MIIP antibody (STJA0008139)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human IIP45
General Information
| Short Description | Rabbit polyclonal anti-Migration and invasion-inhibitory protein for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MIIP |
| Gene ID | 60672 |
| Uniprot ID | MIIP_HUMAN |
| Immunogen | Synthesized peptide derived from human IIP45 |
| Specificity | This antibody detects endogenous levels of IIP45 at Human, Mouse, Rat |
Additional Info
| Post Translational Modifications | Isoform 2 is degraded by the ubiquitin-proteasome pathway. |
| Function | Inhibits glioma cells invasion and down-regulates adhesion- and motility-associated genes such as NFKB2 and ICAM1. Exhibits opposing effects to IGFBP2 on cell invasion. |
| Protein Name | Migration And Invasion-Inhibitory ProteinIgfbp2-Binding ProteinInvasion-Inhibitory Protein 45Iip45 |
| Database Links | |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Migration And Invasion-Inhibitory Protein antibodyAnti-Igfbp2-Binding Protein antibodyAnti-Invasion-Inhibitory Protein 45 antibodyAnti-Iip45 antibodyAnti-MIIP antibodyAnti-IIP45 antibody |
Information sourced from Uniprot.org