Anti-MIF antibody [R04-5K1] (STJA0036393)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human MIF
General Information
| Short Description | Rabbit monoclonal anti-MIF for use in WB, IP and FC in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IP/FC |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R04-5K1 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Chromatography |
| Dilution Range | WB 1:500-1:1000IP 1:50FC 1:50-1:100 |
| Formulation | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | MIF |
| Gene ID | 4282 |
| Uniprot ID | MIF_HUMAN |
| Immunogen | A synthesized peptide derived from human MIF |
Additional Info
| Function | Pro-inflammatory cytokine involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity. |
| Protein Name | Macrophage Migration Inhibitory FactorMifGlycosylation-Inhibiting FactorGifL-Dopachrome IsomeraseL-Dopachrome TautomerasePhenylpyruvate Tautomerase |
| Database Links | Reactome: R-HSA-202733Reactome: R-HSA-6798695Reactome: R-HSA-8950505 |
| Cellular Localisation | SecretedCytoplasmDoes Not Have A Cleavable Signal Sequence And Is Secreted Via A SpecializedNon-Classical PathwaySecreted By Macrophages Upon Stimulation By Bacterial Lipopolysaccharide (Lps)Or By MTuberculosis Antigens |
| Alternative Antibody Names | Anti-Macrophage Migration Inhibitory Factor antibodyAnti-Mif antibodyAnti-Glycosylation-Inhibiting Factor antibodyAnti-Gif antibodyAnti-L-Dopachrome Isomerase antibodyAnti-L-Dopachrome Tautomerase antibodyAnti-Phenylpyruvate Tautomerase antibodyAnti-MIF antibodyAnti-GLIF antibodyAnti-MMIF antibody |
Information sourced from Uniprot.org