Anti-MIEN1 antibody (1-50) (STJ503553)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenMultiple epitope synthetic peptide taken within amino acid regions 1-50, 20-70, 40-90 and 80-130 on human XTP4 protein.
General Information
| Short Description | Rabbit polyclonal antibody anti-MIEN1 (1-50) is suitable for use in ELISA and Western Blot research applications. |
| Applications | ELISA/WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.65-0.83 ยตg/ยตl |
| Purification | Affinity Purified |
| Dilution Range | WB: 1:500-1:1, 000DB: 1:2, 000ELISA: 1:2, 000 |
| Formulation | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Storage Instruction | Store at-20ยฐC for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | MIEN1 |
| Gene ID | 84299 |
| Uniprot ID | MIEN1_HUMAN |
| Immunogen | Multiple epitope synthetic peptide taken within amino acid regions 1-50, 20-70, 40-90 and 80-130 on human XTP4 protein. |
| Immunogen Region | 1-50 |
Additional Info
| Tissue Specificity | Among normal tissues, present only in Leydig cells. Strongly up-regulated in breast cancers and in brain cancer distant metastasis (at protein level). Up-regulated in prostate cancer cells and in the higher grades of prostate adenocarcinoma (at protein level). |
| Post Translational Modifications | Isoprenylation facilitates association with the plasma membrane and enhances the migratory phenotype of cells by inducing increased filopodia formation. |
| Function | Increases cell migration by inducing filopodia formation at the leading edge of migrating cells. Plays a role in regulation of apoptosis, possibly through control of CASP3. May be involved in a redox-related process. |
| Protein Name | Migration And Invasion Enhancer 1Hbv X-Transactivated Gene 4 ProteinHbv Xag-Transactivated Protein 4Protein C35 |
| Cellular Localisation | CytoplasmCytosolCell MembraneLipid-AnchorCytoplasmic SideConcentrates At The Leading Edge Of Migrating CellsLocalizes Outside Membrane Raft Regions |
| Alternative Antibody Names | Anti-Migration And Invasion Enhancer 1 antibodyAnti-Hbv X-Transactivated Gene 4 Protein antibodyAnti-Hbv Xag-Transactivated Protein 4 antibodyAnti-Protein C35 antibodyAnti-MIEN1 antibodyAnti-C17orf37 antibodyAnti-RDX12 antibodyAnti-XTP4 antibody |
Information sourced from Uniprot.org