Anti-MIA2 antibody (361-410 aa) (STJ98610)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from MIA2 at the amino acid range 361-410
General Information
| Short Description | Rabbit polyclonal anti-Melanoma inhibitory activity protein 2 (361-410 aa) for use in WB and IHC in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000IHC-P 1:50-300 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MIA2 |
| Gene ID | 4253 |
| Uniprot ID | MIA2_HUMAN |
| Immunogen | Synthesized peptide derived from MIA2 at the amino acid range 361-410 |
| Immunogen Region | 361-410 aa |
| Specificity | MIA2 Polyclonal Antibody detects endogenous levels of MIA2 |
Additional Info
| Function | Plays a role in the transport of cargos that are too large to fit into COPII-coated vesicles and require specific mechanisms to be incorporated into membrane-bound carriers and exported from the endoplasmic reticulum. Plays a role in the secretion of lipoproteins, pre-chylomicrons and pre-VLDLs, by participating in their export from the endoplasmic reticulum. Thereby, may play a role in cholesterol and triglyceride homeostasis. Required for collagen VII (COL7A1) secretion by loading COL7A1 into transport carriers and recruiting PREB/SEC12 at the endoplasmic reticulum exit sites. |
| Protein Name | Melanoma Inhibitory Activity Protein 2Mia Protein 2Ctage Family Member 5 Er Export FactorCutaneous T-Cell Lymphoma-Associated Antigen 5Meningioma-Expressed Antigen 6/11 |
| Database Links | Reactome: R-HSA-5694530 |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Membrane ProteinLocalizes To Endoplasmic Reticulum Exit Sites (Eres)Also Known As Transitional Endoplasmic Reticulum (Ter) |
| Alternative Antibody Names | Anti-Melanoma Inhibitory Activity Protein 2 antibodyAnti-Mia Protein 2 antibodyAnti-Ctage Family Member 5 Er Export Factor antibodyAnti-Cutaneous T-Cell Lymphoma-Associated Antigen 5 antibodyAnti-Meningioma-Expressed Antigen 6/11 antibodyAnti-MIA2 antibodyAnti-CTAGE5 antibodyAnti-MEA11 antibodyAnti-MEA6 antibodyAnti-MGEA11 antibodyAnti-MGEA6 antibody |
Information sourced from Uniprot.org