| Function | Plays a role in the transport of cargos that are too large to fit into COPII-coated vesicles and require specific mechanisms to be incorporated into membrane-bound carriers and exported from the endoplasmic reticulum. Plays a role in the secretion of lipoproteins, pre-chylomicrons and pre-VLDLs, by participating in their export from the endoplasmic reticulum. Thereby, may play a role in cholesterol and triglyceride homeostasis. Required for collagen VII (COL7A1) secretion by loading COL7A1 into transport carriers and recruiting PREB/SEC12 at the endoplasmic reticulum exit sites. |
| Protein Name | Melanoma Inhibitory Activity Protein 2Mia Protein 2Ctage Family Member 5 Er Export FactorCutaneous T-Cell Lymphoma-Associated Antigen 5Meningioma-Expressed Antigen 6/11 |
| Database Links | Reactome: R-HSA-5694530 |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Membrane ProteinLocalizes To Endoplasmic Reticulum Exit Sites (Eres)Also Known As Transitional Endoplasmic Reticulum (Ter) |
| Alternative Antibody Names | Anti-Melanoma Inhibitory Activity Protein 2 antibodyAnti-Mia Protein 2 antibodyAnti-Ctage Family Member 5 Er Export Factor antibodyAnti-Cutaneous T-Cell Lymphoma-Associated Antigen 5 antibodyAnti-Meningioma-Expressed Antigen 6/11 antibodyAnti-MIA2 antibodyAnti-CTAGE5 antibodyAnti-MEA11 antibodyAnti-MEA6 antibodyAnti-MGEA11 antibodyAnti-MGEA6 antibody |
Information sourced from Uniprot.org
