Anti-MIA/CD-RAP antibody (Internal) (STJ72945)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-MIA/CD-RAP (Internal) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Applications | Pep-ELISA/WB/IHC |
| Host | Goat |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:64000.WB: Approx 14kDa band observed in Human Glioma lysates (calculated MW of 14.5kDa according to NP_006524.1). Recommended concentration: 1-3µg/ml. Primary incubation was 1 hour.IHC: Par |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | MIA |
| Gene ID | 8190 |
| Uniprot ID | MIA_HUMAN |
| Accession Number | NP_006524.1 |
| Immunogen Region | Internal |
| Immunogen Sequence | PKLADRKLCADQE |
| Specificity | The immunizing peptide represents the N terminus of the mature protein. Reported variants represent identical protein: NP_006524.1, NP_001189482.1 |
Additional Info
| Post Translational Modifications | May possess two intramolecular disulfide bonds. |
| Function | Elicits growth inhibition on melanoma cells in vitro as well as some other neuroectodermal tumors, including gliomas. |
| Protein Name | Melanoma-Derived Growth Regulatory ProteinMelanoma Inhibitory Activity Protein |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Melanoma-Derived Growth Regulatory Protein antibodyAnti-Melanoma Inhibitory Activity Protein antibodyAnti-MIA antibody |
Information sourced from Uniprot.org