Anti-MGMT antibody [SRM14655] (STJ11109385)

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STJ11109385
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Host: Rabbit
Applications: WB/IHC-P/IF/ICC/ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Monoclonal
Clone ID : SRM14655
Conjugation: Unconjugated
Isotype: IgG
Purification: Affinity purification
Dilution Range: WB, 1:10000-1:40000
IHC-P, 1:50-1:200
IF/ICC, 1:50-1:200
ELISA, Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MGMT
Gene ID: 4255
Uniprot ID: MGMT_HUMAN
Immunogen: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Function Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
Protein Name Methylated-Dna--Protein-Cysteine Methyltransferase
6-O-Methylguanine-Dna Methyltransferase
Mgmt
O-6-Methylguanine-Dna-Alkyltransferase
Database Links Reactome: R-HSA-5657655
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Methylated-Dna--Protein-Cysteine Methyltransferase antibody
Anti-6-O-Methylguanine-Dna Methyltransferase antibody
Anti-Mgmt antibody
Anti-O-6-Methylguanine-Dna-Alkyltransferase antibody
Anti-MGMT antibody

Information sourced from Uniprot.org

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