Anti-MGMT antibody [IHC090] (STJA0042212)

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STJA0042212
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Short Description :Mouse monoclonal anti-MGMT for use in IHC-p in Human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:IHC-p
Host:Mouse
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :IHC090
Conjugation:Unconjugated
Formulation:Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
Storage Instruction:Store at 2-8°C for up to 1 year. Do not freeze.
Gene Symbol:MGMT
Gene ID:4255
Uniprot ID:MGMT_HUMAN
Specificity:Tested and validated on tonsil, brain tissue.
Function Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
Protein Name Methylated-Dna--Protein-Cysteine Methyltransferase
6-O-Methylguanine-Dna Methyltransferase
Mgmt
O-6-Methylguanine-Dna-Alkyltransferase
Database Links Reactome: R-HSA-5657655
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Methylated-Dna--Protein-Cysteine Methyltransferase antibody
Anti-6-O-Methylguanine-Dna Methyltransferase antibody
Anti-Mgmt antibody
Anti-O-6-Methylguanine-Dna-Alkyltransferase antibody
Anti-MGMT antibody

Information sourced from Uniprot.org

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