Anti-MGAT5B antibody (STJA0008205)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human MGAT5B
General Information
| Short Description | Rabbit polyclonal anti-Alpha-1, 6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MGAT5B |
| Gene ID | 146664 |
| Uniprot ID | MGT5B_HUMAN |
| Immunogen | Synthesized peptide derived from human MGAT5B |
| Specificity | This antibody detects endogenous levels of MGAT5B at Human, Mouse |
Additional Info
| Function | Glycosyltransferase that acts on alpha-linked mannose of N-glycans and O-mannosyl glycans. Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to the beta 1-6 linkage of the mannose residue of GlcNAc-beta1,2-Man-alpha on both the alpha1,3- and alpha1,6-linked mannose arms in the core structure of N-glycan. Also acts on the GlcNAc-beta1,2-Man-alpha1-Ser/Thr moiety, forming a 2,6-branched structure in brain O-mannosyl glycan. Plays an active role in modulating integrin and laminin-dependent adhesion and migration of neuronal cells via its activity in the O-mannosyl glycan pathway. |
| Protein Name | Alpha-1 -6-Mannosylglycoprotein 6-Beta-N-Acetylglucosaminyltransferase BAlpha-Mannoside Beta-1 -6-N-Acetylglucosaminyltransferase BGlcnac-T VbGnt-VbHgntvbMannoside Acetylglucosaminyltransferase 5bN-Acetylglucosaminyl-Transferase VbN-Acetylglucosaminyltransferase IxGnt-Ix |
| Database Links | |
| Cellular Localisation | Golgi Apparatus MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Alpha-1 -6-Mannosylglycoprotein 6-Beta-N-Acetylglucosaminyltransferase B antibodyAnti-Alpha-Mannoside Beta-1 -6-N-Acetylglucosaminyltransferase B antibodyAnti-Glcnac-T Vb antibodyAnti-Gnt-Vb antibodyAnti-Hgntvb antibodyAnti-Mannoside Acetylglucosaminyltransferase 5b antibodyAnti-N-Acetylglucosaminyl-Transferase Vb antibodyAnti-N-Acetylglucosaminyltransferase Ix antibodyAnti-Gnt-Ix antibodyAnti-MGAT5B antibodyAnti-KIAA2008 antibody |
Information sourced from Uniprot.org