| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MGAT1 |
| Gene ID: | 4245 |
| Uniprot ID: | MGAT1_HUMAN |
| Immunogen Region: | 156-445 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 156-445 of human MGAT1 (NP_001108092.1). |
| Immunogen Sequence: | GSAVTHIRQPDLSSIAVPPD HRKFQGYYKIARHYRWALGQ VFRQFRFPAAVVVEDDLEVA PDFFEYFRATYPLLKADPSL WCVSAWNDNGKEQMVDASRP ELLYRTDFFPGLGWLLLAEL WAELEPKWPKAFWDDWMRRP EQRQGRACIRPEISRTMTFG RKGVSHGQFFDQHLKFIKLN QQFVHFTQLDLSYLQREAYD RDFLARVYGAPQLQVEKVRT NDRKELGEVRVQYTGRDSF |
| Function | Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans. |
| Protein Name | Alpha-1 -3-Mannosyl-Glycoprotein 2-Beta-N-Acetylglucosaminyltransferase N-Glycosyl-Oligosaccharide-Glycoprotein N-Acetylglucosaminyltransferase I Gnt-I Glcnac-T I |
| Database Links | Reactome: R-HSA-964739 Reactome: R-HSA-9683686 Reactome: R-HSA-9694548 |
| Cellular Localisation | Golgi Apparatus Membrane Single-Pass Type Ii Membrane Protein Cytoplasm Perinuclear Region Co-Localizes With Bri3 Isoform 1 At The Perinuclear Region |
| Alternative Antibody Names | Anti-Alpha-1 -3-Mannosyl-Glycoprotein 2-Beta-N-Acetylglucosaminyltransferase antibody Anti-N-Glycosyl-Oligosaccharide-Glycoprotein N-Acetylglucosaminyltransferase I antibody Anti-Gnt-I antibody Anti-Glcnac-T I antibody Anti-MGAT1 antibody Anti-GGNT1 antibody Anti-GLCT1 antibody Anti-GLYT1 antibody Anti-MGAT antibody |
Information sourced from Uniprot.org