Anti-MFGE8 antibody (STJ192169)

SKU:
STJ192169
€58.80 - €313.20
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Short Description :Rabbit polyclonal anti-Lactadherin for use in WB and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB/ELISA
Host:Rabbit
Reactivity:Human/Mouse/Rat
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Range:WB 1:500-2000
ELISA 1:5000-20000
Formulation:Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:MFGE8
Gene ID:4240
Uniprot ID:MFGM_HUMAN
Immunogen:Synthesized peptide derived from part of the human protein
Specificity:MFGM Polyclonal Antibody detects endogenous levels of protein.
Post Translational Modifications Medin has a ragged N-terminus with minor species starting at Pro-264 and Gly-273.
Function Plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing. Promotes VEGF-dependent neovascularization. Contributes to phagocytic removal of apoptotic cells in many tissues. Specific ligand for the alpha-v/beta-3 and alpha-v/beta-5 receptors. Also binds to phosphatidylserine-enriched cell surfaces in a receptor-independent manner. Zona pellucida-binding protein which may play a role in gamete interaction. Medin: Main constituent of aortic medial amyloid.
Protein Name Lactadherin
Breast Epithelial Antigen Ba46
Hmfg
Mfgm
Milk Fat Globule-Egf Factor 8
Mfg-E8
Sed1 Cleaved Into - Lactadherin Short Form - Medin
Database Links Reactome: R-HSA-381426
Reactome: R-HSA-8957275
Reactome: R-HSA-977225
Cellular Localisation Membrane
Peripheral Membrane Protein
Secreted
Cytoplasmic Vesicle
Secretory Vesicle
Acrosome Membrane
Located In The Acrosomal Region Of Zona-Pellucida Bound Sperm
Alternative Antibody Names Anti-Lactadherin antibody
Anti-Breast Epithelial Antigen Ba46 antibody
Anti-Hmfg antibody
Anti-Mfgm antibody
Anti-Milk Fat Globule-Egf Factor 8 antibody
Anti-Mfg-E8 antibody
Anti-Sed1 Cleaved Into - Lactadherin Short Form - Medin antibody
Anti-MFGE8 antibody

Information sourced from Uniprot.org