| Host: |
Rabbit |
| Applications: |
WB/IF/ICC/ELISA |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:1000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
TMT1B |
| Gene ID: |
196410 |
| Uniprot ID: |
TMT1B_HUMAN |
| Immunogen Region: |
165-244 |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 165-244 of human METTL7B (NP_689850.2). |
| Immunogen Sequence: |
RPGGVLFFWEHVAEPYGSWA FMWQQVFEPTWKHIGDGCCL TRETWKDLENAQFSEIQMER QPPPLKWLPVGPHIMGKAVK |
| Tissue Specificity | Expressed in the liver. |
| Function | Thiol S-methyltransferase that catalyzes the transfer of a methyl group from S-adenosyl-L-methionine to alkyl and phenolic thiol-containing acceptor substrates. Together with TMT1B accounts for most of S-thiol methylation activity in the endoplasmic reticulum of hepatocytes. Selectively methylates S-centered nucleophiles from metabolites such as hydrogen sulfide and dithiothreitol. |
| Protein Name | Thiol S-Methyltransferase Tmt1bMethyltransferase-Like Protein 7bThiol S-Methyltransferase Mettl7b |
| Cellular Localisation | Endoplasmic Reticulum MembranePeripheral Membrane ProteinLipid DropletMicrosomeCytoplasmCytosolHighly Concentrated In The Perinuclear Area Of The Endoplasmic Reticulum (Er) And Surrounding Lipid DropletsMay Be Associated With The Specific Regions Of The Lr That Form Lipid Droplets And Targeted To The Initial Deposits Of Lipids Where The Lipid Droplets Form |
| Alternative Antibody Names | Anti-Thiol S-Methyltransferase Tmt1b antibodyAnti-Methyltransferase-Like Protein 7b antibodyAnti-Thiol S-Methyltransferase Mettl7b antibodyAnti-TMT1B antibodyAnti-METTL7B antibodyAnti-UNQ594 antibodyAnti-PRO1180 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
