Anti-METTL5 antibody (59-109) (STJA0006326)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human METL5 AA range: 59-109
General Information
| Short Description | Rabbit polyclonal anti-rRNA N6-adenosine-methyltransferase METTL5 (59-109) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:1000-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | METTL5 |
| Gene ID | 29081 |
| Uniprot ID | METL5_HUMAN |
| Immunogen | Synthesized peptide derived from human METL5 AA range: 59-109 |
| Immunogen Region | 59-109 |
| Specificity | This antibody detects endogenous levels of human METL5 |
Additional Info
| Function | Catalytic subunit of a heterodimer with TRMT112, which specifically methylates the 6th position of adenine in position 1832 of 18S rRNA. N6-methylation of adenine(1832) in 18S rRNA resides in the decoding center of 18S rRNA and is required for translation and embryonic stem cells (ESCs) pluripotency and differentiation. |
| Protein Name | Rrna N(6-Adenosine-Methyltransferase Mettl5Methyltransferase-Like Protein 5 |
| Database Links | |
| Cellular Localisation | NucleusPresynapsePostsynapse |
| Alternative Antibody Names | Anti-Rrna N(6-Adenosine-Methyltransferase Mettl5 antibodyAnti-Methyltransferase-Like Protein 5 antibodyAnti-METTL5 antibodyAnti-DC3 antibodyAnti-HSPC133 antibody |
Information sourced from Uniprot.org