Anti-METTL18 antibody (STJA0007987)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human C1orf156
General Information
| Short Description | Rabbit polyclonal anti-Histidine protein methyltransferase 1 homolog for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | METTL18 |
| Gene ID | 92342 |
| Uniprot ID | MET18_HUMAN |
| Immunogen | Synthesized peptide derived from human C1orf156 |
| Specificity | This antibody detects endogenous levels of C1orf156 at Human, Mouse, Rat |
Additional Info
| Function | Protein-L-histidine N-tele-methyltransferase that specifically monomethylates RPL3, thereby regulating translation elongation. Histidine methylation of RPL3 regulates translation elongation by slowing ribosome traversal on tyrosine codons: slower elongation provides enough time for proper folding of synthesized proteins and prevents cellular aggregation of tyrosine-rich proteins. |
| Protein Name | Histidine Protein Methyltransferase 1 HomologArsenic-Transactivated Protein 2Astp2Methyltransferase-Like Protein 18 |
| Database Links | |
| Cellular Localisation | CytoplasmCytosolNucleusNucleolus |
| Alternative Antibody Names | Anti-Histidine Protein Methyltransferase 1 Homolog antibodyAnti-Arsenic-Transactivated Protein 2 antibodyAnti-Astp2 antibodyAnti-Methyltransferase-Like Protein 18 antibodyAnti-METTL18 antibodyAnti-ASTP2 antibodyAnti-C1orf156 antibody |
Information sourced from Uniprot.org