Anti-MESP2 antibody (220-300 aa) (STJ190209)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human protein at the amino acid range 220-300
General Information
| Short Description | Rabbit polyclonal anti-Mesoderm posterior protein 2 (220-300 aa) for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MESP2 |
| Gene ID | 145873 |
| Uniprot ID | MESP2_HUMAN |
| Immunogen | Synthesized peptide derived from the human protein at the amino acid range 220-300 |
| Immunogen Region | 220-300 aa |
| Specificity | MESP2 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Transcription factor with important role in somitogenesis. Defines the rostrocaudal patterning of the somite by participating in distinct Notch pathways. Also regulates the FGF signaling pathway. Specifies the rostral half of the somites. Generates rostro-caudal polarity of somites by down-regulating in the presumptive rostral domain DLL1, a Notch ligand. Participates in the segment border formation by activating in the anterior presomitic mesoderm LFNG, a negative regulator of DLL1-Notch signaling. Acts as a strong suppressor of Notch activity. Together with MESP1 is involved in the epithelialization of somitic mesoderm and in the development of cardiac mesoderm. |
| Protein Name | Mesoderm Posterior Protein 2Class C Basic Helix-Loop-Helix Protein 6Bhlhc6 |
| Database Links | Reactome: R-HSA-9824272 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Mesoderm Posterior Protein 2 antibodyAnti-Class C Basic Helix-Loop-Helix Protein 6 antibodyAnti-Bhlhc6 antibodyAnti-MESP2 antibodyAnti-BHLHC6 antibodyAnti-SCDO2 antibody |
Information sourced from Uniprot.org