Anti-MEOX2 antibody (151-200) (STJ94186)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from human MEOX2. AA range:151-200
General Information
| Short Description | Rabbit polyclonal anti-Homeobox protein MOX-2 (151-200) for use in WB, IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:10000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MEOX2 |
| Gene ID | 4223 |
| Uniprot ID | MEOX2_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from human MEOX2. AA range:151-200 |
| Immunogen Region | 151-200 |
| Specificity | MOX-2 Polyclonal Antibody detects endogenous levels of MOX-2 protein. |
Additional Info
| Function | Mesodermal transcription factor that plays a key role in somitogenesis and somitogenesis and limb muscle differentiation. Required during limb development for normal appendicular muscle formation and for the normal regulation of myogenic genes. May have a regulatory role when quiescent vascular smooth muscle cells reenter the cell cycle. Also acts as a negative regulator of angiogenesis. Activates expression of CDKN1A and CDKN2A in endothelial cells, acting as a regulator of vascular cell proliferation. While it activates CDKN1A in a DNA-dependent manner, it activates CDKN2A in a DNA-independent manner. Together with TCF15, regulates transcription in heart endothelial cells to regulate fatty acid transport across heart endothelial cells. |
| Protein Name | Homeobox Protein Mox-2Growth Arrest-Specific HomeoboxMesenchyme Homeobox 2 |
| Database Links | |
| Cellular Localisation | NucleusNucleus Speckle |
| Alternative Antibody Names | Anti-Homeobox Protein Mox-2 antibodyAnti-Growth Arrest-Specific Homeobox antibodyAnti-Mesenchyme Homeobox 2 antibodyAnti-MEOX2 antibodyAnti-GAX antibodyAnti-MOX2 antibody |
Information sourced from Uniprot.org