| Host: |
Rabbit |
| Applications: |
WB/ICC |
| Reactivity: |
Chicken/Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Memo (N-Term) is suitable for use in Western Blot and Immunocytochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS + 1 mg/ml BSA, 0.05% NaN3 and 50% glycerol |
| Purification: |
Antigen Affinity Purified |
| Dilution Range: |
WB 1:1000IHCICC 1:200IP |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MEMO1 |
| Gene ID: |
51072 |
| Uniprot ID: |
MEMO1_HUMAN |
| Immunogen Region: |
N-Term |
| Specificity: |
The antibody detects a significant 33 kDa* protein corresponding to the molecular mass of Memo on SDS-PAGE immunoblots of mouse heart, mouse C2C12, and rabbit spleen fibroblasts. |
| Immunogen: |
Memo synthetic peptide (coupled to KLH) corresponding to amino acid residues in the N-terminal region of human Memo. This peptide sequence is highly conserved in rat, mouse, and chicken Memo. |
| Function | May control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton. Mediator of ERBB2 signaling. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization. Is required for breast carcinoma cell migration. |
| Protein Name | Protein Memo1C21orf19-Like ProteinHepatitis C Virus Ns5a-Transactivated Protein 7Hcv Ns5a-Transactivated Protein 7Mediator Of Erbb2-Driven Cell Motility 1Mediator Of Cell Motility 1Memo-1 |
| Database Links | Reactome: R-HSA-6785631 |
| Alternative Antibody Names | Anti-Protein Memo1 antibodyAnti-C21orf19-Like Protein antibodyAnti-Hepatitis C Virus Ns5a-Transactivated Protein 7 antibodyAnti-Hcv Ns5a-Transactivated Protein 7 antibodyAnti-Mediator Of Erbb2-Driven Cell Motility 1 antibodyAnti-Mediator Of Cell Motility 1 antibodyAnti-Memo-1 antibodyAnti-MEMO1 antibodyAnti-C2orf4 antibodyAnti-MEMO antibodyAnti-NS5ATP7 antibodyAnti-CGI-27 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
