| Host: | Rabbit |
| Applications: | IHC/WB |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Melanopsin (2-70) is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Lyophilised |
| Purification: | IgG purified |
| Dilution Range: | IHC, WB. A dilution of 1:300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Storage Instruction: | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: | Opn4 |
| Gene ID: | 30044 |
| Uniprot ID: | OPN4_MOUSE |
| Immunogen Region: | 2-70 |
| Specificity: | Specific for Melanopsin. |
| Immunogen: | A synthetic peptide from aa region 2-70 of mouse melanopsin conjugated to an immunogenic carrier protein was used as the antigen. |
| Function | Photoreceptor that binds cis-retinaldehydes. Contributes to pupillar reflex, photoentrainment and other non-image forming responses to light. May be involved in the optokinetic visual tracking response. May be involved in the regulation of retinal hyaloid vessel growth and regression. |
| Protein Name | MelanopsinOpsin-4 |
| Database Links | Reactome: R-MMU-416476Reactome: -MMU-419771 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinCell ProjectionAxonDendritePerikaryon |
| Alternative Antibody Names | Anti-Melanopsin antibodyAnti-Opsin-4 antibodyAnti-Opn4 antibodyAnti-Mop antibodyAnti-Mopn antibody |
Information sourced from Uniprot.org