Anti-MEIOC antibody (218-268 aa) (STJ193680)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human CQ104 at the amino acid range 218-268
General Information
| Short Description | Rabbit polyclonal anti-Meiosis-specific coiled-coil domain-containing protein MEIOC (218-268 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MEIOC |
| Gene ID | 284071 |
| Uniprot ID | MEIOC_HUMAN |
| Immunogen | Synthesized peptide derived from the human CQ104 at the amino acid range 218-268 |
| Immunogen Region | 218-268 aa |
| Specificity | This antibody detects endogenous levels of CQ104 at Human/Mouse |
Additional Info
| Function | Is required for meiosis completion in both male and female germ cells. Confers stability to numerous meiotic mRNAs in gonads allowing proper initiation and progression into meiosis prophase I. The function may involve YTHDC2 and is independent of induction by retinoic acid (RA). Maintains an extended meiotic prophase I by properly promoting the transition from a mitotic to a meiotic cell cycle program by binding transcripts through its interaction with YTHDC2 that regulate the mitotic cell cycle. |
| Protein Name | Meiosis-Specific Coiled-Coil Domain-Containing Protein MeiocMeiosis-Specific With Coiled-Coil Domain Protein |
| Database Links | |
| Cellular Localisation | CytoplasmNucleusAt Late Pachytene A Fraction Is Nuclear |
| Alternative Antibody Names | Anti-Meiosis-Specific Coiled-Coil Domain-Containing Protein Meioc antibodyAnti-Meiosis-Specific With Coiled-Coil Domain Protein antibodyAnti-MEIOC antibodyAnti-C17orf104 antibody |
Information sourced from Uniprot.org