Anti-MED7 antibody (1-233) (STJ118528)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal MED7 (1-233) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MED7 |
| Gene ID | 9443 |
| Uniprot ID | MED7_HUMAN |
| Immunogen Region | 1-233 |
| Immunogen Sequence | MGEPQQVSALPPPPMQYIKE YTDENIQEGLAPKPPPPIKD SYMMFGNQFQCDDLIIRPLE SQGIERLHPMQFDHKKELRK LNMSILINFLDLLDILIRSP GSIKREEKLEDLKLLFVHVH HLINEYRPHQARETLRVMME VQKRQRLETAERFQKHLERV IEMIQNCLASLPDDLPHSEA GMRVKTEPMDADDSNNCTGQ NEHQRENSGHRRDQIIEKDA ALCVLIDEMNERP |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-233 of human MED7 (NP_004261.1). |
Additional Info
| Post Translational Modifications | Constitutively sumoylated. |
| Function | Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. |
| Protein Name | Mediator Of Rna Polymerase Ii Transcription Subunit 7Hmed7Activator-Recruited Cofactor 34 Kda ComponentArc34Cofactor Required For Sp1 Transcriptional Activation Subunit 9Crsp Complex Subunit 9Mediator Complex Subunit 7Rna Polymerase Transcriptional Regulation Mediator Subunit 7 HomologTranscriptional Coactivator Crsp33 |
| Database Links | Reactome: R-HSA-1989781Reactome: R-HSA-212436Reactome: R-HSA-381340Reactome: R-HSA-9833110Reactome: R-HSA-9841922 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Mediator Of Rna Polymerase Ii Transcription Subunit 7 antibodyAnti-Hmed7 antibodyAnti-Activator-Recruited Cofactor 34 Kda Component antibodyAnti-Arc34 antibodyAnti-Cofactor Required For Sp1 Transcriptional Activation Subunit 9 antibodyAnti-Crsp Complex Subunit 9 antibodyAnti-Mediator Complex Subunit 7 antibodyAnti-Rna Polymerase Transcriptional Regulation Mediator Subunit 7 Homolog antibodyAnti-Transcriptional Coactivator Crsp33 antibodyAnti-MED7 antibodyAnti-ARC34 antibodyAnti-CRSP9 antibody |
Information sourced from Uniprot.org