Anti-MED4 antibody (1-270) (STJ111586)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal MED4 (1-270) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:200-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MED4 |
| Gene ID | 29079 |
| Uniprot ID | MED4_HUMAN |
| Immunogen Region | 1-270 |
| Immunogen Sequence | MAASSSGEKEKERLGGGLGV AGGNSTRERLLSALEDLEVL SRELIEMLAISRNQKLLQAG EENQVLELLIHRDGEFQELM KLALNQGKIHHEMQVLEKEV EKRDSDIQQLQKQLKEAEQI LATAVYQAKEKLKSIEKARK GAISSEEIIKYAHRISASNA VCAPLTWVPGDPRRPYPTDL EMRSGLLGQMNNPSTNGVNG HLPGDALAAGRLPDVLAPQY PWQSNDMSMNMLPPNHSSD |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human MED4 (NP_054885.1). |
Additional Info
| Function | Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. |
| Protein Name | Mediator Of Rna Polymerase Ii Transcription Subunit 4Activator-Recruited Cofactor 36 Kda ComponentArc36Mediator Complex Subunit 4Trap/Smcc/Pc2 Subunit P36 SubunitVitamin D3 Receptor-Interacting Protein Complex 36 Kda ComponentDrip36 |
| Database Links | Reactome: R-HSA-1989781Reactome: R-HSA-212436Reactome: R-HSA-381340Reactome: R-HSA-9833110Reactome: R-HSA-9841922 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Mediator Of Rna Polymerase Ii Transcription Subunit 4 antibodyAnti-Activator-Recruited Cofactor 36 Kda Component antibodyAnti-Arc36 antibodyAnti-Mediator Complex Subunit 4 antibodyAnti-Trap/Smcc/Pc2 Subunit P36 Subunit antibodyAnti-Vitamin D3 Receptor-Interacting Protein Complex 36 Kda Component antibodyAnti-Drip36 antibodyAnti-MED4 antibodyAnti-ARC36 antibodyAnti-DRIP36 antibodyAnti-VDRIP antibodyAnti-HSPC126 antibody |
Information sourced from Uniprot.org