| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-MED4 (1-270) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:200-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MED4 |
| Gene ID: |
29079 |
| Uniprot ID: |
MED4_HUMAN |
| Immunogen Region: |
1-270 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human MED4 (NP_054885.1). |
| Immunogen Sequence: |
MAASSSGEKEKERLGGGLGV AGGNSTRERLLSALEDLEVL SRELIEMLAISRNQKLLQAG EENQVLELLIHRDGEFQELM KLALNQGKIHHEMQVLEKEV EKRDSDIQQLQKQLKEAEQI LATAVYQAKEKLKSIEKARK GAISSEEIIKYAHRISASNA VCAPLTWVPGDPRRPYPTDL EMRSGLLGQMNNPSTNGVNG HLPGDALAAGRLPDVLAPQY PWQSNDMSMNMLPPNHSSD |
| Function | Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. |
| Protein Name | Mediator Of Rna Polymerase Ii Transcription Subunit 4Activator-Recruited Cofactor 36 Kda ComponentArc36Mediator Complex Subunit 4Trap/Smcc/Pc2 Subunit P36 SubunitVitamin D3 Receptor-Interacting Protein Complex 36 Kda ComponentDrip36 |
| Database Links | Reactome: R-HSA-1989781Reactome: R-HSA-212436Reactome: R-HSA-381340 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Mediator Of Rna Polymerase Ii Transcription Subunit 4 antibodyAnti-Activator-Recruited Cofactor 36 Kda Component antibodyAnti-Arc36 antibodyAnti-Mediator Complex Subunit 4 antibodyAnti-Trap/Smcc/Pc2 Subunit P36 Subunit antibodyAnti-Vitamin D3 Receptor-Interacting Protein Complex 36 Kda Component antibodyAnti-Drip36 antibodyAnti-MED4 antibodyAnti-ARC36 antibodyAnti-DRIP36 antibodyAnti-VDRIP antibodyAnti-HSPC126 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
