| Host: |
Rabbit |
| Applications: |
WB/IF |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-MED25 (30-200) is suitable for use in Western Blot and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000IF/ICC 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MED25 |
| Gene ID: |
81857 |
| Uniprot ID: |
MED25_HUMAN |
| Immunogen Region: |
30-200 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 30-200 of human MED25 (NP_112235.2). |
| Immunogen Sequence: |
PYFEGLRKHYLLPAIEYFNG GPPAETDFGGDYGGTQYSLV VFNTVDCAPESYVQCHAPTS SAYEFVTWLDGIKFMGGGGE SCSLIAEGLSTALQLFDDFK KMREQIGQTHRVCLLICNSP PYLLPAVESTTYSGCTTENL VQQIGERGIHFSIVSPRKLP ALRLLFEKAAP |
| Tissue Specificity | Ubiquitously expressed. Highest levels in brain, heart, kidney, peripheral leukocytes, placenta, skeletal muscle and spleen. |
| Function | Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Required for RARA/RXRA-mediated transcription. |
| Protein Name | Mediator Of Rna Polymerase Ii Transcription Subunit 25Activator Interaction Domain-Containing Protein 1Activator-Recruited Cofactor 92 Kda ComponentArc92Mediator Complex Subunit 25P78 |
| Database Links | Reactome: R-HSA-1989781Reactome: R-HSA-212436Reactome: R-HSA-381340 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Mediator Of Rna Polymerase Ii Transcription Subunit 25 antibodyAnti-Activator Interaction Domain-Containing Protein 1 antibodyAnti-Activator-Recruited Cofactor 92 Kda Component antibodyAnti-Arc92 antibodyAnti-Mediator Complex Subunit 25 antibodyAnti-P78 antibodyAnti-MED25 antibodyAnti-ACID1 antibodyAnti-ARC92 antibodyAnti-PTOV2 antibodyAnti-TCBAP0758 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
