Anti-MED14 antibody (701-750 aa) (STJ92486)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human MED14 at the amino acid range 701-750
General Information
| Short Description | Rabbit polyclonal anti-Mediator of RNA polymerase II transcription subunit 14 (701-750 aa) for use in IHC, IF and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | IHC 1:100-1:300IF 1:200-1:1000ELISA 1:40000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MED14 |
| Gene ID | 9282 |
| Uniprot ID | MED14_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human MED14 at the amino acid range 701-750 |
| Immunogen Region | 701-750 aa |
| Specificity | CRSP150 Polyclonal Antibody detects endogenous levels of CRSP150 protein. |
Additional Info
| Function | Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. |
| Protein Name | Mediator Of Rna Polymerase Ii Transcription Subunit 14Activator-Recruited Cofactor 150 Kda ComponentArc150Cofactor Required For Sp1 Transcriptional Activation Subunit 2Crsp Complex Subunit 2Mediator Complex Subunit 14Rgr1 HomologHrgr1Thyroid Hormone Receptor-Associated Protein Complex 170 Kda ComponentTrap170Transcriptional Coactivator Crsp150Vitamin D3 Receptor-Interacting Protein Complex 150 Kda ComponentDrip150 |
| Database Links | Reactome: R-HSA-1989781Reactome: R-HSA-212436Reactome: R-HSA-381340Reactome: R-HSA-9833110Reactome: R-HSA-9841922 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Mediator Of Rna Polymerase Ii Transcription Subunit 14 antibodyAnti-Activator-Recruited Cofactor 150 Kda Component antibodyAnti-Arc150 antibodyAnti-Cofactor Required For Sp1 Transcriptional Activation Subunit 2 antibodyAnti-Crsp Complex Subunit 2 antibodyAnti-Mediator Complex Subunit 14 antibodyAnti-Rgr1 Homolog antibodyAnti-Hrgr1 antibodyAnti-Thyroid Hormone Receptor-Associated Protein Complex 170 Kda Component antibodyAnti-Trap170 antibodyAnti-Transcriptional Coactivator Crsp150 antibodyAnti-Vitamin D3 Receptor-Interacting Protein Complex 150 Kda Component antibodyAnti-Drip150 antibodyAnti-MED14 antibodyAnti-ARC150 antibodyAnti-CRSP2 antibodyAnti-CXorf4 antibodyAnti-DRIP150 antibodyAnti-EXLM1 antibodyAnti-RGR1 antibodyAnti-TRAP170 antibody |
Information sourced from Uniprot.org