Anti-MED13L antibody (361-375) (STJ73066)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-MED13L (361-375) is suitable for use in ELISA research applications. |
| Applications | Pep-ELISA |
| Host | Goat |
| Reactivity | Human/Dog/Pig/Cow |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:128000.WB: Preliminary experiments gave an approx 80kDa band in lysates of cell line HeLa after 1µg/ml antibody staining. Please note that currently we cannot find an explanation in the literatu |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | MED13L |
| Gene ID | 23389 |
| Uniprot ID | MD13L_HUMAN |
| Accession Number | NP_056150.1 |
| Immunogen Region | 361-375 |
| Immunogen Sequence | SPKRSGKIPPKLHNH |
Additional Info
| Function | Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. This subunit may specifically regulate transcription of targets of the Wnt signaling pathway and SHH signaling pathway. |
| Protein Name | Mediator Of Rna Polymerase Ii Transcription Subunit 13-LikeMediator Complex Subunit 13-LikeThyroid Hormone Receptor-Associated Protein 2Thyroid Hormone Receptor-Associated Protein Complex 240 Kda Component-Like |
| Database Links | Reactome: R-HSA-1989781Reactome: R-HSA-381340Reactome: R-HSA-9833110 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Mediator Of Rna Polymerase Ii Transcription Subunit 13-Like antibodyAnti-Mediator Complex Subunit 13-Like antibodyAnti-Thyroid Hormone Receptor-Associated Protein 2 antibodyAnti-Thyroid Hormone Receptor-Associated Protein Complex 240 Kda Component-Like antibodyAnti-MED13L antibodyAnti-KIAA1025 antibodyAnti-PROSIT240 antibodyAnti-THRAP2 antibodyAnti-TRAP240L antibody |
Information sourced from Uniprot.org