Anti-MDH2 antibody (59-338) (STJ115477)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal MDH2 (59-338) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MDH2 |
| Gene ID | 4191 |
| Uniprot ID | MDHM_HUMAN |
| Immunogen Region | 59-338 |
| Immunogen Sequence | AHTPGVAADLSHIETKAAVK GYLGPEQLPDCLKGCDVVVI PAGVPRKPGMTRDDLFNTNA TIVATLTAACAQHCPEAMIC VIANPVNSTIPITAEVFKKH GVYNPNKIFGVTTLDIVRAN TFVAELKGLDPARVNVPVIG GHAGKTIIPLISQCTPKVDF PQDQLTALTGRIQEAGTEVV KAKAGAGSATLSMAYAGARF VFSLVDAMNGKEGVVECSFV KSQETECTYFSTPLLLGKK |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 59-338 of human MDH2 (NP_005909.2). |
Additional Info
| Post Translational Modifications | Acetylation is enhanced by up to 67% after treatment either with trichostin A (TSA) or with nicotinamide (NAM) with the appearance of tri- and tetraacetylations. Glucose also increases acetylation by about 60%. |
| Protein Name | Malate Dehydrogenase - Mitochondrial |
| Database Links | Reactome: R-HSA-71403Reactome: R-HSA-9837999Reactome: R-HSA-9856872 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Antibody Names | Anti-Malate Dehydrogenase - Mitochondrial antibodyAnti-MDH2 antibody |
Information sourced from Uniprot.org