• STJ72967 (0. 01µg/ml) staining of Human (A) , Mouse (B) and Rat (C) Heart lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • STJ72967 (0. 01µg/ml) staining of Pig Heart lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-MDH1/MOR2 antibody (Internal) (STJ72967)

SKU:
STJ72967-100

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Host: Goat
Applications: Pep-ELISA/WB
Reactivity: Human/Mouse/Rat/Dog/Pig/Cow
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-MDH1/MOR2 (Internal) is suitable for use in ELISA and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: WB-0.01-0.03µg/ml
ELISA-antibody detection limit dilution 1:128000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: MDH1
Gene ID: 4190
Uniprot ID: MDHC_HUMAN
Immunogen Region: Internal
Accession Number: NP_001186040.1; NP_005908.1; NP_001186041.1
Specificity: This antibody is expected to recognize all reported isoforms (NP_001186040.1; NP_005908.1; NP_001186041.1).
Immunogen Sequence: TNCLTASKSAPSIPK
Function Catalyzes the reduction of aromatic alpha-keto acids in the presence of NADH. Plays essential roles in the malate-aspartate shuttle and the tricarboxylic acid cycle, important in mitochondrial NADH supply for oxidative phosphorylation. Catalyzes the reduction of 2-oxoglutarate to 2-hydroxyglutarate, leading to elevated reactive oxygen species (ROS).
Protein Name Malate Dehydrogenase - Cytoplasmic
Aromatic Alpha-Keto Acid Reductase
Kar
Cytosolic Malate Dehydrogenase
Database Links Reactome: R-HSA-70263
Cellular Localisation Cytoplasm
Cytosol
Alternative Antibody Names Anti-Malate Dehydrogenase - Cytoplasmic antibody
Anti-Aromatic Alpha-Keto Acid Reductase antibody
Anti-Kar antibody
Anti-Cytosolic Malate Dehydrogenase antibody
Anti-MDH1 antibody
Anti-MDHA antibody

Information sourced from Uniprot.org

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