MDH1 antibody western blot HeLa lysates STJA0037190

Anti-MDH1 antibody [R03-2T1] (STJA0037190)

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STJA0037190
€160.20 - €337.80
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Short Description :Rabbit monoclonal anti-MDH1 for use in WB, ICC, IF, IP and FC in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB/ICC/IF/IP/FC
Host:Rabbit
Reactivity:Human/Mouse/Rat
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :R03-2T1
Isotype:IgG
Conjugation:Unconjugated
Purification:Affinity Purified
Dilution Range:WB 1:500-1:1000
IF 1:50-1:200
IP 1:50
FC 1:50-1:100
Formulation:Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Instruction:Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol:MDH1
Gene ID:4190
Uniprot ID:MDHC_HUMAN
Immunogen:A synthesized peptide derived from human MDH1
Post Translational Modifications ISGylated. Acetylation at Lys-118 dramatically enhances enzymatic activity and promotes adipogenic differentiation.
Function Catalyzes the reduction of aromatic alpha-keto acids in the presence of NADH. Plays essential roles in the malate-aspartate shuttle and the tricarboxylic acid cycle, important in mitochondrial NADH supply for oxidative phosphorylation. Catalyzes the reduction of 2-oxoglutarate to 2-hydroxyglutarate, leading to elevated reactive oxygen species (ROS).
Protein Name Malate Dehydrogenase - Cytoplasmic
Aromatic Alpha-Keto Acid Reductase
Kar
Cytosolic Malate Dehydrogenase
Database Links Reactome: R-HSA-9856872
Cellular Localisation Cytoplasm
Cytosol
Alternative Antibody Names Anti-Malate Dehydrogenase - Cytoplasmic antibody
Anti-Aromatic Alpha-Keto Acid Reductase antibody
Anti-Kar antibody
Anti-Cytosolic Malate Dehydrogenase antibody
Anti-MDH1 antibody
Anti-MDHA antibody

Information sourced from Uniprot.org

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