Anti-MCP-1 antibody [MNA.1] (STJ16100753)

Clonality:	Monoclonal
Clone ID:	MNA.1
Conjugation:	Unconjugated
Isotype:	IgG1
Formulation:	PBS with 0.1% BSA and 0.02% sodium azide
Concentration:	100 ug/mL
Storage Instruction:	Store at 2-8°C upon receipt.

Gene Symbol:	CCL2
Gene ID:	6347
Uniprot ID:	CCL2_HUMAN

Tissue Specificity	Expressed in the seminal plasma, endometrial fluid and follicular fluid (at protein level). Expressed in monocytes.
Post Translational Modifications	Processing at the N-terminus can regulate receptor and target cell selectivity. Deletion of the N-terminal residue converts it from an activator of basophil to an eosinophil chemoattractant. N-Glycosylated.
Function	Acts as a ligand for C-C chemokine receptor CCR2. Signals through binding and activation of CCR2 and induces a strong chemotactic response and mobilization of intracellular calcium ions. Exhibits a chemotactic activity for monocytes and basophils but not neutrophils or eosinophils. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis.
Protein Name	C-C Motif Chemokine 2 Hc11 Monocyte Chemoattractant Protein 1 Monocyte Chemotactic And Activating Factor Mcaf Monocyte Chemotactic Protein 1 Mcp-1 Monocyte Secretory Protein Je Small-Inducible Cytokine A2
Database Links	Reactome: R-HSA-380108 Reactome: R-HSA-380994 Reactome: R-HSA-6783783 Reactome: R-HSA-6785807
Cellular Localisation	Secreted
Alternative Antibody Names	Anti-C-C Motif Chemokine 2 antibody Anti-Hc11 antibody Anti-Monocyte Chemoattractant Protein 1 antibody Anti-Monocyte Chemotactic And Activating Factor antibody Anti-Mcaf antibody Anti-Monocyte Chemotactic Protein 1 antibody Anti-Mcp-1 antibody Anti-Monocyte Secretory Protein Je antibody Anti-Small-Inducible Cytokine A2 antibody Anti-CCL2 antibody Anti-MCP1 antibody Anti-SCYA2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance