Anti-MCCC1 antibody (620-670 aa) (STJ195538)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human MCCA at the amino acid range 620-670
General Information
| Short Description | Rabbit polyclonal anti-Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial (620-670 aa) for use in WB and IHC in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000IHC-P 1:50-300 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MCCC1 |
| Gene ID | 56922 |
| Uniprot ID | MCCA_HUMAN |
| Immunogen | Synthesized peptide derived from the human MCCA at the amino acid range 620-670 |
| Immunogen Region | 620-670 aa |
| Specificity | This antibody detects endogenous levels of MCCA at Human/Mouse/Rat |
Additional Info
| Function | Biotin-attachment subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3-methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric acid catabolism. |
| Protein Name | Methylcrotonoyl-Coa Carboxylase Subunit Alpha - MitochondrialMccase Subunit Alpha3-Methylcrotonyl-Coa Carboxylase 13-Methylcrotonyl-Coa Carboxylase Biotin-Containing Subunit3-Methylcrotonyl-Coa -Carbon Dioxide Ligase Subunit Alpha |
| Database Links | Reactome: R-HSA-196780Reactome: R-HSA-3371599Reactome: R-HSA-70895Reactome: R-HSA-9909438 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Antibody Names | Anti-Methylcrotonoyl-Coa Carboxylase Subunit Alpha - Mitochondrial antibodyAnti-Mccase Subunit Alpha antibodyAnti-3-Methylcrotonyl-Coa Carboxylase 1 antibodyAnti-3-Methylcrotonyl-Coa Carboxylase Biotin-Containing Subunit antibodyAnti-3-Methylcrotonyl-Coa -Carbon Dioxide Ligase Subunit Alpha antibodyAnti-MCCC1 antibodyAnti-MCCA antibody |
Information sourced from Uniprot.org