Anti-MC4R antibody (10-60) (STJ501732)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthetic peptide taken within amino acid region 10-60 on human MC4R protein.
General Information
| Short Description | Rabbit polyclonal antibody anti-MC4R (10-60) is suitable for use in ELISA, Immunohistochemistry, Immunoprecipitation and Western Blot research applications. |
| Applications | ELISA/IHC/IP/WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.55-0.75 ยตg/ยตl |
| Purification | Affinity Purified |
| Dilution Range | WB: 1:500DB: 1:10, 000ELISA: 1:10, 000IP: 1:200IHC: 1:100 |
| Formulation | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Storage Instruction | Store at-20ยฐC for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | MC4R |
| Gene ID | 4160 |
| Uniprot ID | MC4R_HUMAN |
| Immunogen | Synthetic peptide taken within amino acid region 10-60 on human MC4R protein. |
| Immunogen Region | 10-60 |
Additional Info
| Tissue Specificity | Brain, placental, and gut tissues. |
| Function | Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. Plays a central role in energy homeostasis and somatic growth. This receptor is mediated by G proteins that stimulate adenylate cyclase (cAMP). |
| Protein Name | Melanocortin Receptor 4Mc4-R |
| Database Links | Reactome: R-HSA-375276Reactome: R-HSA-418555Reactome: R-HSA-9856649 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Melanocortin Receptor 4 antibodyAnti-Mc4-R antibodyAnti-MC4R antibody |
Information sourced from Uniprot.org