Anti-MC3R antibody (1-120) (STJ113214)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal MC3R (1-120) antibody for use in WB and ELISA in mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MC3R |
| Gene ID | 4159 |
| Uniprot ID | MC3R_HUMAN |
| Immunogen Region | 1-120 |
| Immunogen Sequence | MNASCCLPSVQPTLPNGSEH LQAPFFSNQSSSAFCEQVFI KPEVFLSLGIVSLLENILVI LAVVRNGNLHSPMYFFLCSL AVADMLVSVSNALETIMIAI VHSDYLTFEDQFIQHMDNIF |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human MC3R (NP_063941.3). |
Additional Info
| Tissue Specificity | Brain, placental, and gut tissues. |
| Function | Receptor for MSH (alpha, beta and gamma) and ACTH. This receptor is mediated by G proteins which activate adenylate cyclase. Required for expression of anticipatory patterns of activity and wakefulness during periods of limited nutrient availability and for the normal regulation of circadian clock activity in the brain. |
| Protein Name | Melanocortin Receptor 3Mc3-R |
| Database Links | Reactome: R-HSA-375276Reactome: R-HSA-418555Reactome: R-HSA-9856649 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Melanocortin Receptor 3 antibodyAnti-Mc3-R antibodyAnti-MC3R antibody |
Information sourced from Uniprot.org