Anti-MC1R antibody [R01-3K6] (STJA0036968)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human MC1 Receptor
General Information
| Short Description | Rabbit monoclonal anti-MC1R for use in WB and IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R01-3K6 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Chromatography |
| Dilution Range | WB 1:500-1:1000IHC 1:50-1:100 |
| Formulation | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | MC1R |
| Gene ID | 4157 |
| Uniprot ID | MSHR_HUMAN |
| Immunogen | A synthesized peptide derived from human MC1 Receptor |
Additional Info
| Tissue Specificity | Expressed in melanocytes. Expressed in corticoadrenal tissue. |
| Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Mediates melanogenesis, the production of eumelanin (black/brown) and phaeomelanin (red/yellow), via regulation of cAMP signaling in melanocytes. |
| Protein Name | Melanocyte-Stimulating Hormone ReceptorMsh-RMelanocortin Receptor 1Mc1-R |
| Database Links | Reactome: R-HSA-375276Reactome: R-HSA-418555Reactome: R-HSA-9856649 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Melanocyte-Stimulating Hormone Receptor antibodyAnti-Msh-R antibodyAnti-Melanocortin Receptor 1 antibodyAnti-Mc1-R antibodyAnti-MC1R antibodyAnti-MSHR antibody |
Information sourced from Uniprot.org