| Short Description : | Rabbit monoclonal anti-MC-2 for use in WB and IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC-P |
| Host: | Rabbit |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | R31-2P-1 |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Purification: | Affinity Chromatography |
| Dilution Range: | WB 1:500-1:1000IHC 1:100-1:200 |
| Formulation: | Liquid in PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction: | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
| Gene Symbol: | MC5R |
| Gene ID: | 4161 |
| Uniprot ID: | MC5R_HUMAN |
| Immunogen: | A synthesized peptide derived from human MC5 Receptor |
| Tissue Specificity | Expressed in the brain but not in the melanoma cells. |
| Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. This receptor is a possible mediator of the immunomodulation properties of melanocortins. |
| Protein Name | Melanocortin Receptor 5Mc5-RMc-2 |
| Database Links | Reactome: R-HSA-375276Reactome: R-HSA-418555Reactome: R-HSA-9856649 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Melanocortin Receptor 5 antibodyAnti-Mc5-R antibodyAnti-Mc-2 antibodyAnti-MC5R antibody |
Information sourced from Uniprot.org
