Anti-MBOAT4 antibody (STJA0004708)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthetic peptide of human MBOAT4
General Information
| Short Description | Rabbit polyclonal anti-Ghrelin O-Acyltransferase for use in IHC and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.9 mg/mL |
| Purification | Antigen affinity purification |
| Dilution Range | IHC 1:30-1:150 |
| Formulation | PBS with 0.05% NaN3 and 40% Glycerol, pH7.4 |
| Storage Instruction | Store at-20°C for the long term, and avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | MBOAT4 |
| Gene ID | 619373 |
| Uniprot ID | MBOA4_HUMAN |
| Immunogen | Synthetic peptide of human MBOAT4 |
Additional Info
| Tissue Specificity | Expressed predominantly in stomach with moderate levels in pancreas and relatively low levels in most other tissues. |
| Post Translational Modifications | Not glycosylated. |
| Function | Catalyzes ghrelin acylation at 'Ser-3' using preferentially octanoyl-CoA, hexanoyl-CoA and decanoyl-CoA as acyl-CoA donors leading to ghrelin activity. In vitro also uses acyl-CoA donors of different lengths from short-chain (C2) to long-chain fatty acids (C16) knowing that acyl-CoA donors from butanoyl-CoA (C4) to dodecanoyl-CoA (C12) are more efficient compared to longer acyl-CoA donors, such as myristoyl-CoA (C14) and palmitoyl-CoA (C16) that are not efficient. |
| Protein Name | Membrane-Bound Ghrelin O-Acyltransferase Mboat4Membrane-Bound O-Acyltransferase Domain-Containing Protein 4O-Acyltransferase Domain-Containing Protein 4 |
| Database Links | Reactome: R-HSA-422085 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Membrane-Bound Ghrelin O-Acyltransferase Mboat4 antibodyAnti-Membrane-Bound O-Acyltransferase Domain-Containing Protein 4 antibodyAnti-O-Acyltransferase Domain-Containing Protein 4 antibodyAnti-MBOAT4 antibodyAnti-GOAT antibodyAnti-OACT4 antibodyAnti-FKSG89 antibody |
Information sourced from Uniprot.org