Tissue Specificity | Expressed in various myeloid cell lines, detected in brain and lung. |
Function | Could play a significant role in the signal transduction of hematopoietic cells. May regulate tyrosine kinase activity of SRC-family members in brain by specifically phosphorylating their C-terminal regulatory tyrosine residue which acts as a negative regulatory site. It may play an inhibitory role in the control of T-cell proliferation. |
Protein Name | Megakaryocyte-Associated Tyrosine-Protein KinaseCsk Homologous KinaseChkHematopoietic Consensus Tyrosine-Lacking KinaseProtein Kinase HylTyrosine-Protein Kinase Ctk |
Database Links | Reactome: R-HSA-8863795 |
Cellular Localisation | CytoplasmMembraneIn Platelets90% Of Matk Localizes To The Membrane FractionAnd Translocates To The Cytoskeleton Upon Thrombin Stimulation |
Alternative Antibody Names | Anti-Megakaryocyte-Associated Tyrosine-Protein Kinase antibodyAnti-Csk Homologous Kinase antibodyAnti-Chk antibodyAnti-Hematopoietic Consensus Tyrosine-Lacking Kinase antibodyAnti-Protein Kinase Hyl antibodyAnti-Tyrosine-Protein Kinase Ctk antibodyAnti-MATK antibodyAnti-CTK antibodyAnti-HYL antibody |
Information sourced from Uniprot.org