Anti-MATK antibody (352-466) (STJ28734)

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STJ28734
€132.60 - €606.60
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Applications:WB/IHC-P/ELISA
Host:Rabbit
Reactivity:Human/Mouse/Rat
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:Lot specific
Purification:Affinity purification
Dilution Range:WB:1:500-1:2000
IHC-P:1:50-1:200
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation:PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:MATK
Gene ID:4145
Uniprot ID:MATK_HUMAN
Immunogen Region:352-466
Immunogen Sequence:PEALKHGKFTSKSDVWSFGV LLWEVFSYGRAPYPKMSLKE VSEAVEKGYRMEPPEGCPGP VHVLMSSCWEAEPARRPPFR KLAEKLARELRSAGAPASVS GQDADGSTSPRSQEP
Specificity:Recombinant fusion protein containing a sequence corresponding to amino acids 352-466 of human MATK (NP_647611.1).
Tissue Specificity Expressed in various myeloid cell lines, detected in brain and lung.
Function Could play a significant role in the signal transduction of hematopoietic cells. May regulate tyrosine kinase activity of SRC-family members in brain by specifically phosphorylating their C-terminal regulatory tyrosine residue which acts as a negative regulatory site. It may play an inhibitory role in the control of T-cell proliferation.
Protein Name Megakaryocyte-Associated Tyrosine-Protein Kinase
Csk Homologous Kinase
Chk
Hematopoietic Consensus Tyrosine-Lacking Kinase
Protein Kinase Hyl
Tyrosine-Protein Kinase Ctk
Database Links Reactome: R-HSA-8863795
Cellular Localisation Cytoplasm
Membrane
In Platelets
90% Of Matk Localizes To The Membrane Fraction
And Translocates To The Cytoskeleton Upon Thrombin Stimulation
Alternative Antibody Names Anti-Megakaryocyte-Associated Tyrosine-Protein Kinase antibody
Anti-Csk Homologous Kinase antibody
Anti-Chk antibody
Anti-Hematopoietic Consensus Tyrosine-Lacking Kinase antibody
Anti-Protein Kinase Hyl antibody
Anti-Tyrosine-Protein Kinase Ctk antibody
Anti-MATK antibody
Anti-CTK antibody
Anti-HYL antibody

Information sourced from Uniprot.org