| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | S3MR |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:3000-1:18000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MAT2A |
| Gene ID: | 4144 |
| Uniprot ID: | METK2_HUMAN |
| Immunogen Region: | 1-100 |
| Immunogen Sequence: | MNGQLNGFHEAFIEEGTFLF TSESVGEGHPDKICDQISDA VLDAHLQQDPDAKVACETVA KTGMILLAGEITSRAAVDYQ KVVREAVKHIGYDDSSKGFD |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MAT2A (P31153). |
| Tissue Specificity | Detected in kidney. |
| Function | Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate. |
| Protein Name | S-Adenosylmethionine Synthase Isoform Type-2Adomet Synthase 2Methionine Adenosyltransferase 2Mat 2Methionine Adenosyltransferase IiMat-Ii |
| Database Links | Reactome: R-HSA-156581 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-S-Adenosylmethionine Synthase Isoform Type-2 antibodyAnti-Adomet Synthase 2 antibodyAnti-Methionine Adenosyltransferase 2 antibodyAnti-Mat 2 antibodyAnti-Methionine Adenosyltransferase Ii antibodyAnti-Mat-Ii antibodyAnti-MAT2A antibodyAnti-AMS2 antibodyAnti-MATA2 antibody |
Information sourced from Uniprot.org
![Western blot analysis of lysates from wild type (WT) and GPX4 knockdown (KD) U-87 MG cell pools, using [KD Validated] GPX4 Rabbit monoclonal antibody (STJ11101303) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/90216/359234/STJ11101303_1__60787.1713123659.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and GPX4 knockdown (KD) U-87 MG cell pools, using [KD Validated] GPX4 Rabbit monoclonal antibody (STJ11101303) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.")
