Anti-MAT1A antibody [R09-9C8] (STJA0034545)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide of human MAT1A
General Information
| Short Description | Rabbit monoclonal anti-MAT1A for use in WB and IP in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IP |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R09-9C8 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.3 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000IP 1:20 |
| Formulation | 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | MAT1A |
| Gene ID | 4143 |
| Uniprot ID | METK1_HUMAN |
| Immunogen | A synthetic peptide of human MAT1A |
Additional Info
| Tissue Specificity | Expressed in liver. |
| Post Translational Modifications | S-nitrosylation of Cys-120 inactivates the enzyme. An intrachain disulfide bond can be formed. The protein structure shows that the relevant Cys residues are in a position that would permit formation of a disulfide bond. |
| Function | Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate. |
| Protein Name | S-Adenosylmethionine Synthase Isoform Type-1Adomet Synthase 1Methionine Adenosyltransferase 1Mat 1Methionine Adenosyltransferase I/IiiMat-I/Iii |
| Database Links | Reactome: R-HSA-156581Reactome: R-HSA-1614635Reactome: R-HSA-2408508Reactome: R-HSA-5579024 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-S-Adenosylmethionine Synthase Isoform Type-1 antibodyAnti-Adomet Synthase 1 antibodyAnti-Methionine Adenosyltransferase 1 antibodyAnti-Mat 1 antibodyAnti-Methionine Adenosyltransferase I/Iii antibodyAnti-Mat-I/Iii antibodyAnti-MAT1A antibodyAnti-AMS1 antibodyAnti-MATA1 antibody |
Information sourced from Uniprot.org