![Anti-Mast cell tryptase antibody [SM0416] (STJA0010416)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/180313/403966/STJA0010416_1__76962.1738950935.jpg?c=1 "Anti-Mast cell tryptase antibody [SM0416] (STJA0010416)")
![Anti-Mast cell tryptase antibody [SM0416] (STJA0010416)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/180313/403967/STJA0010416_2__63452.1738950936.jpg?c=1 "Anti-Mast cell tryptase antibody [SM0416] (STJA0010416)")
![Anti-Mast cell tryptase antibody [SM0416] (STJA0010416)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/180313/403968/STJA0010416_3__90683.1738950937.jpg?c=1 "Anti-Mast cell tryptase antibody [SM0416] (STJA0010416)")
![Anti-Mast cell tryptase antibody [SM0416] (STJA0010416)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/180313/403969/STJA0010416_4__80564.1738950937.jpg?c=1 "Anti-Mast cell tryptase antibody [SM0416] (STJA0010416)")
![Anti-Mast cell tryptase antibody [SM0416] (STJA0010416)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/180313/403966/STJA0010416_1__76962.1738950935.jpg?c=1 "Anti-Mast cell tryptase antibody [SM0416] (STJA0010416)")
Anti-Mast cell tryptase antibody [SM0416] (STJA0010416)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2bk
ImmunogenRecombinant protein corresponding to Human Mast cell tryptase
General Information
| Short Description | Mouse monoclonal anti-Mast cell tryptase for use in IHC and IF in Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/IF |
| Host | Mouse |
| Reactivity | Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SM0416 |
| Isotype | IgG2bk |
| Conjugation | Unconjugated |
| Purification | Affinity purification |
| Dilution Range | IHC/IF (R) 1:500-1:1000 |
| Formulation | PBS with 0.15% ProClin300, 100 Mu g/mL BSA and 50% glycerol. |
| Storage Instruction | Store at-20C for up to one year, and avoid repeated freeze-thaw cycles. |
Target Information
| Gene Symbol | TPSAB1 |
| Gene ID | 7177 |
| Uniprot ID | TRYB1_HUMAN |
| Immunogen | Recombinant protein corresponding to Human Mast cell tryptase |
Additional Info
| Function | Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. Isoform 2 cleaves large substrates, such as fibronectin, more efficiently than isoform 1, but seems less efficient toward small substrates. |
| Protein Name | Tryptase Alpha/Beta-1Tryptase-1Tryptase ITryptase Alpha-1 |
| Database Links | Reactome: R-HSA-1592389 |
| Cellular Localisation | SecretedReleased From The Secretory Granules Upon Mast Cell Activation |
| Alternative Antibody Names | Anti-Tryptase Alpha/Beta-1 antibodyAnti-Tryptase-1 antibodyAnti-Tryptase I antibodyAnti-Tryptase Alpha-1 antibodyAnti-TPSAB1 antibodyAnti-TPS1 antibodyAnti-TPS2 antibodyAnti-TPSB1 antibody |
Information sourced from Uniprot.org