• Western blot analysis of various lysates using MARVELD2 Rabbit polyclonal antibody (STJ114486) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.

Anti-MARVELD2 antibody (1-195) (STJ114486)

SKU:
STJ114486

£169.50 - £449.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-MARVELD2 (1-195) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MARVELD2
Gene ID: 153562
Uniprot ID: MALD2_HUMAN
Immunogen Region: 1-195
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-195 of human MARVELD2 (NP_001033692.2).
Immunogen Sequence: MSNDGRSRNRDRRYDEVPSD LPYQDTTIRTHPTLHDSERA VSADPLPPPPLPLQPPFGPD FYSSDTEEPAIAPDLKPVRR FVPDSWKNFFRGKKKDPEWD KPVSDIRYISDGVECSPPAS PARPNHRSPLNSCKDPYGGS EGTFSSRKEADAVFPRDPYG SLDRHTQTVRTYSEKVEEYN LRYSYMKSWAGLLRI
Post Translational Modifications Ubiquitinated by ITCH.but this ubiquitination does not lead to proteasomal degradation. Phosphorylated.
Function Plays a role in the formation of tricellular tight junctions and of epithelial barriers. Required for normal hearing via its role in the separation of the endolymphatic and perilymphatic spaces of the organ of Corti in the inner ear, and for normal survival of hair cells in the organ of Corti.
Protein Name Marvel Domain-Containing Protein 2
Tricellulin
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Cell Junction
Tight Junction
Located At Tricellular Contacts
Alternative Antibody Names Anti-Marvel Domain-Containing Protein 2 antibody
Anti-Tricellulin antibody
Anti-MARVELD2 antibody
Anti-TRIC antibody

Information sourced from Uniprot.org

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