• Western blot analysis of the lysates from K562 cells using MARK3 antibody.
  • Western blot analysis of lysates from HeLa and 293 cells, using MARK3 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of 293 cells using C-TAK1 Polyclonal Antibody diluted at 1：500
  • Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using MARK3 Antibody. The picture on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using C-TAK1 Polyclonal Antibody diluted at 1：500

Anti-MARK3 antibody (1-50 aa) (STJ92512)

SKU:
STJ92512

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-MAP/microtubule affinity-regulating kinase 3 (1-50 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:40000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MARK3
Gene ID: 4140
Uniprot ID: MARK3_HUMAN
Immunogen Region: 1-50 aa
Specificity: C-TAK1 Polyclonal Antibody detects endogenous levels of C-TAK1 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human MARK3 at the amino acid range 1-50
Post Translational Modifications Phosphorylated at Thr-211 by STK11/LKB1 in complex with STE20-related adapter-alpha (STRADA) pseudo kinase and CAB39. Phosphorylation at Thr-564 by PRKCZ/aPKC inhibits the kinase activity.
Function Serine/threonine-protein kinase. Involved in the specific phosphorylation of microtubule-associated proteins for MAP2 and MAP4. Phosphorylates the microtubule-associated protein MAPT/TAU. Phosphorylates CDC25C on 'Ser-216'. Regulates localization and activity of some histone deacetylases by mediating phosphorylation of HDAC7, promoting subsequent interaction between HDAC7 and 14-3-3 and export from the nucleus. Regulates localization and activity of MITF by mediating its phosphorylation, promoting subsequent interaction between MITF and 14-3-3 and retention in the cytosol. Negatively regulates the Hippo signaling pathway and antagonizes the phosphorylation of LATS1. Cooperates with DLG5 to inhibit the kinase activity of STK3/MST2 toward LATS1. Phosphorylates PKP2 and KSR1.
Protein Name Map/Microtubule Affinity-Regulating Kinase 3
C-Tak1
Ctak1
Cdc25c-Associated Protein Kinase 1
Elkl Motif Kinase 2
Emk-2
Protein Kinase Stk10
Ser/Thr Protein Kinase Par-1
Par-1a
Serine/Threonine-Protein Kinase P78
Database Links Reactome: R-HSA-5673000
Reactome: R-HSA-5674135
Reactome: R-HSA-5675221
Reactome: R-HSA-6802946
Reactome: R-HSA-6802948
Reactome: R-HSA-6802952
Reactome: R-HSA-6802955
Reactome: R-HSA-9649948
Reactome: R-HSA-9656223
Cellular Localisation Cell Membrane
Peripheral Membrane Protein
Cell Projection
Dendrite
Cytoplasm
Alternative Antibody Names Anti-Map/Microtubule Affinity-Regulating Kinase 3 antibody
Anti-C-Tak1 antibody
Anti-Ctak1 antibody
Anti-Cdc25c-Associated Protein Kinase 1 antibody
Anti-Elkl Motif Kinase 2 antibody
Anti-Emk-2 antibody
Anti-Protein Kinase Stk10 antibody
Anti-Ser/Thr Protein Kinase Par-1 antibody
Anti-Par-1a antibody
Anti-Serine/Threonine-Protein Kinase P78 antibody
Anti-MARK3 antibody
Anti-CTAK1 antibody
Anti-EMK2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance