Anti-MAPKBP1 antibody (1-100) (STJ24496)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal MAPKBP1 (1-100) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MAPKBP1 |
| Gene ID | 23005 |
| Uniprot ID | MABP1_HUMAN |
| Immunogen Region | 1-100 |
| Immunogen Sequence | MAVEGSTITSRIKNLLRSPS IKLRRSKAGNRREDLSSKVT LEKVLGITVSGGRGLACDPR SGLVAYPAGCVVVLFNPRKH KQHHILNSSRKTITALAFSP |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MAPKBP1 (NP_001122080.1). |
Additional Info
| Tissue Specificity | Expressed in intestinal mucosa, where it is detected in epithelial cells, endothelial cells, smooth muscle cells and immune cells, such as lymphocytes. Expressed in kidney. |
| Function | Negative regulator of NOD2 function. It down-regulates NOD2-induced processes such as activation of NF-kappa-B signaling, IL8 secretion and antibacterial response. Involved in JNK signaling pathway. |
| Protein Name | Mitogen-Activated Protein Kinase-Binding Protein 1Jnk-Binding Protein 1Jnkbp-1 |
| Database Links | |
| Cellular Localisation | CytoplasmNucleusCytoskeletonSpindle PoleNot Detected In The CiliumLocalized Around The Poles Of The Mitotic Spindle From Prophase To Anaphase In Mitotic Cells |
| Alternative Antibody Names | Anti-Mitogen-Activated Protein Kinase-Binding Protein 1 antibodyAnti-Jnk-Binding Protein 1 antibodyAnti-Jnkbp-1 antibodyAnti-MAPKBP1 antibodyAnti-JNKBP1 antibodyAnti-KIAA0596 antibody |
Information sourced from Uniprot.org